Compiling Quixote c extensions for Windows using the mingw compiler: The variable build_extensions in setup.py must be set to True (instead of "sys.platform != win32"). Then, Quixote can be installed through python setup.py build_ext --compiler=mingw32 install The mingw compiler can be downloaded from http://www.bloodshed.net/dev/devcpp.html. Probably you need to list the bin directory (C:\Program files\Dev-Cpp\bin) in the PATH. To permit gcc to link against Python library, you also need a libpython2x.a file. Instructions for its creation are provided at http://sebsauvage.net/python/mingw.html.